Dr Steve Lee
Steve Lee completed his undergraduate training in Engineering at the Nanyang Technological University (Singapore) and a PhD in Optics at Optical Trapping Group at the University of St Andrews (UK) with Prof Kishan Dholakia. During his PhD, he developed new optical manipulation technologies for biological and nanoparticles. He performed the first conclusive nonlinear light measurements on artifical kerr medium and built a multimodality bioworkstation. In 2010, he left the UK to pursue a 2-year postdoctoral training at Wellman Photomedicine/Harvard Medical School (USA) with Prof S H Andy Yun, where he developed adaptive intravital endomicroscopy for live small animal imaging. That is followed by a short stint as a Vice Chancellor Fellow at UNSW on nanowire optical manipulation. In 2013, he started his own research group (Applied Optics Lab) at ANU Research School of Engineering that focus on developing novel optical techniques and instruments to harness light for application in biomedicine and nanotechnology, where he recently won the 2014 ANSTO Eureka Prize for developing low cost elastomer optics. In 2014, he joins ARC Centre of Excellence for Advanced Molecular Imaging as an Associated Investigator to develop the next generation of intravital microscopy for in-vivo imaging. In 2015, he receive an ARC Discovery Early Career Research Award (DECRA). In 2016, he joins ARC Centre of Excellence for Nanoscale Biophotonics as an Associated Investigator.
Current student projects
Recent publications
† Corresponding * Equal contribution
- Kamal, T, Watkins, R, Cen, Z et al 2017, 'Design and fabrication of a passive droplet dispenser for portable high resolution imaging system', Scientific Reports, pp. 1-13pp.
- Li, Y, Gautam, V, Bruestle, A et al 2017, 'Flexible polygon-mirror based laser scanning microscope platform for multiphoton in-vivo imaging', Journal of Biophotonics, vol. -, no. -, pp. 1-12pp.
- He, X, Gaus, K & Lee, W 2017, 'Label-free dynamic volumetric imaging of deforming giant unilamellar vesicles under micro-flows', OSA Biophotonics Congress: The Optics in Today's Life Sciences, Optical Society of American (OSA), America, pp. 1-3pp.
- Li, Y, Huang, H, Burgio, G et al 2017, 'Dynamic control over field of view in polygon mirror-based laser scanning multiphoton microscope', OSA Biophotonics Congress: The Optics in Today's Life Sciences, Optical Society of American (OSA), America.
- Choy, J, Sane, S, Lee, W et al 2017, 'Improving focal photostimulation of cortical neurons with pre-derived wavefront correction', Frontiers in Cellular Neuroscience, vol. 11, no. 105, pp. 1-9pp.
- Fang, Q, Curatolo, A, Wijesinghe, P et al 2017, 'Ultrahigh resolution optical coherence elastography combined with a rigid micro-endoscope', Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI, SPIE, United States of America.
- Fleddermann, R, Lee, W, Huang, K et al 2017, 'Compact flexible multi-pass rotary delay line using spinning micro-machined mirrors', Scientific Reports, vol. 7, no. 9299, pp. 1 - 9pp..
- Kamal, T, Yang, L & Lee, W 2017, 'Application of computational optics in moldless lenses', 3D Image Acquisition and Display: Technology, Perception and Applications, 3D 2017, Conference Organising Committee, TBC, p. 3.
- T McMenamin, W M Lee 2017, 'A compact multi-trap optical tweezer system based on CD-ROM technologies', SPIE Nanoscience and Engineering, SPIE - The International Society for Optical Engineering, United States.
- Kamal, T, Watkins, R, Cen, Z et al 2016, 'Thimble microscope system', SPIE Biophotonics Australasia, ed. M R Hutchinson and E M Goldys, SPIE - The International Society for Optical Engineering, Bellingham, United States.
- Lee, W 2016, 'High Speed Temporal Modulation with Cascaded Fibre Delay Line and Micro-structured Mirrors', Australian Conference on Optical Fibre Technology 2016, Optical Society of American (OSA), Sydney.
- Kamal, T, Watkins, R, Cen, Z et al 2016, 'Direct fabrication of silicone lenses with 3D printed parts', SPIE Biophotonics Australasia, ed. M R Hutchinson and E M Goldys, SPIE - The International Society for Optical Engineering, Bellingham, United States, pp. 1001336 (1-6pp).
- He, X, Nguyen, C, Pratap, M et al 2016, 'Adaptive spatial filtering for off-axis digital holographic microscopy based on region-recognition approach with iterative thresholding', SPIE Biophotonics Australasia, ed. M R Hutchinson and E M Goldys, SPIE - The International Society for Optical Engineering, Bellingham, United States, pp. 7pp.
- Li, Y & Lee, W 2016, 'PScan 1.0: flexible software framework for polygon based multiphoton microscopy', SPIE Biophotonics Australasia, ed. M R Hutchinson and E M Goldys, SPIE - The International Society for Optical Engineering, Bellingham, United States, pp. 6pp.
- He, X, Zheng, Y & Lee, W 2016, 'DHMI: Dynamic holographic microscopy interface', SPIE Biophotonics Australasia, ed. M R Hutchinson and E M Goldys, SPIE - The International Society for Optical Engineering, Bellingham, United States, pp. 8pp.
- Li, Y, Bruestle, A, Gautam, V et al 2016, 'High speed multiphoton imaging', SPIE Biophotonics Australasia, ed. M R Hutchinson and E M Goldys, SPIE - The International Society for Optical Engineering, Bellingham, United States, pp. 5pp.
- Zhu, W, Eckerskorn, N, Upadhya, A et al 2016, 'Dynamic axial control over optically levitating particles in air with an electrically-tunable variable-focus lens', Biomedical Optics Express, vol. 7, no. 7, pp. 2902-2911.
- He, X, Nguyen, C, Pratap, M et al 2016, 'Automated fourier space region-recognition filtering for off-axis digital holographic microscopy', Biomedical Optics Express, vol. 7, no. 8, pp. 3111-3123.
- He, X, Maier, A & Lee, W 2016, 'Mapping the progression of malaria infected erythrocytes with holographic microscopy', Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015, IEEE, TBC, pp. 1-2.
- Kamal, T, He, X & Lee, W 2015, 'Reinventing Pocket Microscopy', Journal of the Royal Microscopical Society, vol. 37, no. 4, pp. 41-43.
- Choi, M, Lee, W & Yun, S 2015, 'Intravital microscopic interrogation of peripheral taste sensation', Scientific Reports, vol. 5, pp. -.
- Lee, W, Wright, D, Watkins, R et al 2015, 'Integrated elastic microscope device', Proceedings of SPIE - International Society for Optical Engineering, vol. 9332.
- Lee, W 2015, 'Miniature droplet lenses for mobile microscopy', SPIE Newsroom, pp. 3pp.
- Kamal, T, He, X & Lee, W 2015, 'Reinventing Pocket Microscopy', Journal of the Royal Microscopical Society, vol. 37, no. 4, pp. 41-43.
- Lee, W, Upadhya, A, Reece, P et al 2014, 'Fabricating Low Cost and High Performance Elastomer Lenses using Hanging Droplets', Biomedical Optics Express, vol. 5, no. 5, pp. 1626-1635.
- L. Li, W. Lee, X. Xie, W. Krolikowski, A. Rode, and J. Zhou, "Shaping self-imaging bottle beams with modified quasi-Bessel beams," Opt. Lett. 39, 2278-2281 (2014).
- Lee, W 2014, 'High Performance, low cost elastomer optics', Optical Fabrication and Testing, OFT 2014, Optics Infobase, USA.
- Lee, W 2014, 'Imaging Cells in Living Animals with Two Photon In-Vivo Abberation-Free Endomicroscopy', Australian Biomedical Engineering Conference ABEC 2014, Engineers Australia, Australia.
- Lee, W 2014, 'Stick-on microscope for smartphones', Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics, ed. G L Coté, SPIE, United States of America, pp. 1-6.
- Lee, W 2014, Frugal microscopy: Inspiring tomorrow's interdisciplinary scientist, pp. 24-25.
- Lee, W 2014, Pocket Pathology, pp. 39-41.
- Lee, W & Kamal, T 2014, A Droplet Approach to Lens Making, pp. 30-31.
- Lee, W, Upadhya, A & Phan, T 2014, 'Mobile microscopy on the move', SPIE Digital Photography X, ed. N Sampat, R Tezaur, S Battiato, B A Fowler, SPIE, USA, pp. 1-7.
- Eckerskorn, N, Kirian, R, Kupper, J et al 2013, 'Hollow Bessel-like beam as an optical guide for a stream of microscopic particles', Optics Express, vol. 21, no. 25, pp. 30492-30499.
- F Wang, W Toe, W.M. Lee et al “Resolving Stable Axial Trapping Points of Nanowires in an Optical Tweezers Using Photoluminescence Mapping" Nanoletters 13 1185-1191 (2013)
- Li, L, Eckerskorn, N, Kirian, R et al 2013, 'Quasi-bessel hollow beam as optical guide for micro-particles', Optical Trapping and Optical Micromanipulation X, SPIE - The International Society for Optical Engineering, San Diego, CA, V.8810, pp.88100N1-88100N11.
- Kim, J, Lee, W, Kim, P et al 2012, 'Fabrication and operation of GRIN probes for in vivo fluorescence cellular imaging of internal organs in small animals', Nature Protocols, vol. 7, pp. 1456-1469.
- Lee, W, Chow, T & Ng, B 2011, 'Resolving inter-particle position and optical forces along the axial direction using optical coherence gating', Bio-Optics: Design and Application, BODA 2011, The Optical Society, Monterey USA.
- Arita, Y, Torres-Mapa, M, Lee, W et al 2011, 'Spatially optimized gene transfection by laser-induced breakdown of optically trapped nanoparticles', Applied Physics Letters, vol. 98, no. 9, pp. 1-4.
- Lee, W & Yun, S 2011, 'Adaptive aberration correction of GRIN lenses for confocal endomicroscopy', Optics Letters, vol. 36, no. 23, pp. 4608-4610.
- Ahluwalia, B & Lee, W 2010, 'Collinear non-diffracting beams: classification and properties', Complex Light and Optical Forces IV, SPIE - The International Society for Optical Engineering, San Francisco, CA, pp. 1-11.
- Shane, J, Mazilu, M, Lee, W et al 2010, 'Effect of pulse temporal shape on optical trapping and impulse transfer using ultrashort pulsed lasers', Optics Express, vol. 18, no. 7, pp. 7554-7568.
- Chow, T, Lee, W, Tan, K et al 2010, 'Resolving interparticle position and optical forces along the axial direction using optical coherence gating', Applied Physics Letters, vol. 97, no. 23, pp. 231113 - 231113-3.
- Mthunzi, P, Lee, W, Riches, A et al 2010, 'Intracellular Dielectric Tagging for Improved Optical Manipulation of Mammalian Cells', IEEE Journal on Selected Topics in Quantum Electronics, vol. 16, no. 3, pp. 608 - 618.
- Tan, K, Mazilu, M, Chow, T et al 2009, 'In-fiber common-path optical coherence tomography using a conical-tip fiber', Optics Express, vol. 17, no. 4, pp. 2375-2384.
- El-Ganainy, R, Christodoulides, D, Wright, E et al 2009, 'Nonlinear optical dynamics in nonideal gases of interacting colloidal nanoparticles', Physical Review A - Atomic, Molecular, and Optical Physics, vol. 80, no. 5, pp. 1-6.
- Lee, W, El-Ganainy, R, Christodoulides, D et al 2009, 'Nonlinear optical response of colloidal suspensions', Optics Express, vol. 17, no. 12, pp. 10277-10289.
- Lee, W, Dholakia, K, Wright, E et al 2009, 'Probing the nonlinear optical response of nanosuspensions', 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009, IEEE, Baltimore, MD, pp. 1-2.
- El-Ganainy, R, Christodoulides, D, Wright, E et al 2009, 'Optical Nonlinearity of a Colloidal "Non-Ideal Gas" of Nano-Suspensions', 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009, IEEE, Baltimore, MD, pp. 1-2.
- Wright, E, Lee, W, Dholakia, K et al 2009, 'Optical nonlinearity of liquid nanosuspensions: Kerr versus exponential model', Optical Trapping and Optical Micromanipulation VI, SPIE - The International Society for Optical Engineering, San Diego, CA, p. 9.
- Lee, W, Hernandez-Pozos, J, Vera-Robles, L et al 2009, 'Dielectric enhanced nanoparticles for three-dimensional optical manipulation', Optical Trapping and Optical Micromanipulation VI, SPIE - The International Society for Optical Engineering, San Diego, CA, pp. 1-9.
- Dholakia, K & Lee, W 2008, 'Optical Trapping Takes Shape: The Use of Structured Light Fields', Advances in Atomic, Molecular and Optical Physics, vol. 56, pp. 261-337.
- Hernandez-Pozos, J, Lee, W, Vera-Robles, L et al 2008, 'Controlled three-dimensional manipulation of vanadium oxide nanotubes with optical tweezers', Applied Physics Letters, vol. 93, no. 34, pp. 243107 - 243107-3.
- Wright, E, Lee, W, Giscard, P et al 2008, 'Long distance beam propagation in colloidal suspensions: Comparison between theory and experiment', Optical Trapping and Optical Micromanipulation V, ed. Kishan Dholakia and Gabriel C. Spalding, SPIE, Bellingham, WA, USA, pp. 1-9.
- Shane, J, Mazilu, M, Lee, W et al 2008, 'Optical trapping using ultrashort 12.9fs pulses', Optical Trapping and Optical Micromanipulation V, ed. Kishan Dholakia and Gabriel C. Spalding, SPIE, Bellingham, WA, USA.
- J. L. Hernandez-Pozos, W. M. Lee, L. I. Vera-Robles, A. Campero, and K. Dholakia, "Controlled three-dimensional manipulation of vanadium oxide nanotubes with optical tweezers," Applied Physics Letters 93, 243107 (2008)
- W. M. Lee, P. J. Reece, R. F. Marchington, N. K. Metzger, and K. Dholakia, "Construction and calibration of an optical trap on a fluorescence optical microscope," Nature Protocols 2, 3226-3238 (2007)
- Harvard-ANU Summer Scholarship Exchange (Convenor/Coordinator)
- PHYS 8014 - Photonics in Biotech and Nanotech (Lecturer)
| Code | Title | Year 20.. | Semester |
|---|---|---|---|
| ENGN3820 | Biomedical Imaging | 16, 17, 18, 19 | S1 |
